Table 4. Interaction analyses between TLR5 gene polymorphisms and Helicobacter pylori infection.
| Helicobacter pylori infection | ||||||
|---|---|---|---|---|---|---|
| No | Yes | |||||
| Case | Control | OR(95% CI)* | Case | Control | OR(95% CI)* | |
| rs5744174 | ||||||
| TT | 285 | 467 | 1.00 (reference) | 509 | 391 | 2.13 (1.75–2.60) |
| TC+CC | 215 | 247 | 1.43 (1.13–1.80) | 291 | 195 | 2.23 (1.87–2.68) |
| P for interaction = 0.114 | ||||||
| rs1640827 | ||||||
| TT | 330 | 515 | 1.00 (reference) | 512 | 386 | 2.07 (1.71–2.50) |
| TC+CC | 170 | 199 | 1.33 (1.04–1.71) | 288 | 200 | 2.13 (1.79–2.53) |
| P for interaction = 0.009 | ||||||
| rs17163737 | ||||||
| GG | 270 | 430 | 1.00 (reference) | 409 | 315 | 2.07 (1.67–2.55) |
| GT+TT | 230 | 284 | 1.29 (1.02–1.62) | 391 | 271 | 2.17 (1.81–2.61) |
| P for interaction = 0.006 | ||||||
*Adjusted for residence, and smoking status