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. 2017 Mar 10;8(19):31101–31111. doi: 10.18632/oncotarget.16088

Figure 2. Maternal exposure to DBP leads to renal fibrosis in adult offspring.

Figure 2

(A) H&E and Masson trichrome stained images of kidneys in the DBP-exposed adult offspring and DBP-unexposed controls. (B) Represented immunohistochemical localization of α-SMA, fibronectin and TGF-β in the kidneys of DBP-exposed adult offspring and unexposed controls. (C) The average optical density of α-SMA, fibronectin and TGF-β in the kidneys of DBP-exposed adult offspring and unexposed controls. (D) Western blot showing different α-SMA, fibronectin and TGF-β protein levels of kidneys in DBP-exposed adult offspring and unexposed controls. (E) Densitometric quantification of α-SMA, fibronectin and TGF-β proteins in the kidneys of DBP-exposed adult offspring and unexposed controls. (F) Real-time PCR assessed the expression of α-SMA (Acta), fibronectin (Fn) and TGF-β (Tgfb) in the kidneys of DBP-exposed adult offspring and unexposed controls. Data represent mean ± SD. n = 6 rats per group, *P < 0.05.