Table 4. Association of prominent SNPs with the gastric cancer based on logistic tests adjusted by gender and age.
| SNP ID | Minor allele | Dominant model | Additive model | Recessive model | |||
|---|---|---|---|---|---|---|---|
| OR (95% CI) | pa | OR (95% CI) | pa | OR (95% CI) | pa | ||
| rs6713088 | G | 1.231 (0.87–1.74) | 0.241 | 1.218 (0.959–1.547) | 0.106 | 1.413 (0.902–2.213) | 0.131 |
| rs11125529 | A | 1.344 (0.951–1.899) | 0.094 | 1.438 (1.073–1.928) | 0.015* | 3.804 (1.47–9.845) | 0.006* |
| rs12615793 | A | 1.348 (0.9586–1.897) | 0.086 | 1.436 (1.078–1.913) | 0.013* | 3.47 (1.428–8.429) | 0.006* |
| rs843711 | T | 1.429 (0.989–2.064) | 0.058 | 1.372 (1.076–1.748) | 0.011* | 1.625 (1.068–2.472) | 0.023* |
| rs11896604 | G | 1.363 (0.9656–1.923) | 0.078 | 1.398 (1.051–1.86) | 0.021* | 2.564 (1.13–5.815) | 0.024* |
| rs843706 | A | 1.404 (0.9669–2.037) | 0.075 | 1.32 (1.033–1.687) | 0.027* | 1.478 (0.9678–2.256) | 0.071 |
| rs17045754 | C | 1.357 (0.96–1.918) | 0.084 | 1.411 (1.051–1.894) | 0.022* | 2.946 (1.182–7.343) | 0.02* |
Abbreviation: SNP: Single nucleotide polymorphisms;
aP values were calculated by Wald test adjusted by gender and age; *P < 0.05 indicates statistical significance;
Bonferroni's multiple adjustment was applied to the level of significance, which was set at P < 0.00078 (0.05/65).