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. 2017 Mar 10;8(19):31238–31253. doi: 10.18632/oncotarget.16114

Figure 4. PP1 inhibits apoptosis in the kidney after I/R injury.

Figure 4

(A) Photomicrographs (×200) display TUNEL staining in the kidney sections of sham and renal I/R injured mice. (B) Positive TUNEL staining cells were counted in 10 high-power fields and expressed as means ± SEM. (C) Kidney tissue lysates were subjected to immunoblot analysis with specific antibodies against cleaved-caspase3, cleaved-PRAP and GAPDH. The expression level of cleaved-caspase3 (D) and (E) cleaved-PRAP were calculated by densitometry and normalized with GAPDH. Scale bar, 50 μm. Data are means ± SEM (n = 6). Means with distinct letter values (A, B) are significantly different from one another (P < 0.05).