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. 2005 Jan 6;24(2):240–250. doi: 10.1038/sj.emboj.7600535

Figure 3.

Figure 3

The dimer interface and properties of the molecular surface of the IMD dimer. (A, B) Molecular contact surface (yellow) of the IMD (A) and amphiphysin BAR domain (B) dimers, calculated using SwissPDB-Viewer (Guex and Peitsch, 1997). (C) Molecular surface of the IMD dimer oriented with the dyad parallel to the viewing direction. The surface area is coloured according to sequence conservation among the five mammalian IMD sequences in Figure 1. The colour shading is based on the Q-score calculated by ClustalX (Thompson et al, 1997), whereby deep blue indicates identity (Q=100). The top and bottom panels show the N- and C-terminal faces of the dimer, respectively. The C in italics on the lower panel indicates the location of the C-termini on the IMD dimer. (D) Molecular surface of the IMD dimer oriented as in panel (C) and coloured according to electrostatic surface potential, colour ramped from −15 kBT/e (red) to +15 kBT/e (blue).