Table 3. Association of BRCA1 and ERCC1 and the effect of chemotherapy in primary nasopharyngeal carcinoma and cervical lymph node.

Expression		Response
In primary		N	CR+PR	SD+PD	RR (%)	X2	P1
BRCA1
+		129	72	57	55.8	6.224	0.013
-		72	53	19	73.6
ERCC1
+		136	77	59	56.6	7.795	0.005
-		65	50	15	76.9
BRCA1	ERCC1
+	+	103	54	49	52.4	12.840	0.005
-	-	39	32	7	82.1
+	-	26	19	7	73.1
-	+	33	23	10	69.6
In cervical lymph node
BRCA1
+		129	86	43	66.6	4.387	0.036
-		72	58	14	80.5
ERCC1
+		136	89	47	65.4	5.496	0.019
-		65	53	12	81.5
BRCA1	ERCC1
+	+	103	62	41	60.1	8.831	0.032
-	-	39	33	6	84.6
+	-	26	20	6	76.9
-	+	33	24	9	72.7

¹Statistical analysis was estimated by χ2 test, and P < 0.05 was considered statistically significant; CR, complete response; PR, partial response; SD, stable disease; PD, progressive disease, RR, response rate.