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. 2017 Feb 21;8(19):31355–31367. doi: 10.18632/oncotarget.15565

Table 4. Association of BRCA1 and ERCC1 and the effect of radiochemotherapy in primary nasopharyngeal carcinoma and cervical lymph node.

Expression Response
In primary N CR PR RR(%) X2 P1
BRCA1
+ 129 106 22 82.1 2.071 0.209
- 72 65 7 90.2
ERCC1
+ 136 113 23 83.1 0.715 0.532
- 65 57 8 87.6
BRCA1 ERCC1
+ + 103 84 19 81.5 4.243 0.218
- - 39 37 2 94.8
+ - 26 23 3 88.4
- + 33 28 4 84.8
In cervical lymph node
BRCA1
+ 129 118 11 91.4 1.356 0.387
- 72 69 3 95
ERCC1
+ 136 123 13 90.4 3.437 0.108
- 65 64 1 98.4
BRCA1 ERCC1
+ + 103 91 12 88 3.370 0.338
- - 39 38 1 97
+ - 26 24 2 92
- + 33 31 2 93

1Statistical analysis was estimated by χ2 test, and P < 0.05 was considered statistically significant; CR, complete response; PR, partial response; RR, response rate.