. 2017 Feb 23;8(19):31435–31448. doi: 10.18632/oncotarget.15634

Table 3. Subgroup analyses.

	ZEB1							ZEB2
	pooled HR	95% CI	p	heterogeneity		p_Begg	p_Egger	pooled HR	95% CI	p	heterogeneity		p_Begg	p_Egger
	pooled HR	95% CI	p	I² (%)	p	p_Begg	p_Egger	pooled HR	95% CI	p	I² (%)	p	p_Begg	p_Egger
cancer type
pancreatic cancer	1.487	(1.071, 2.064)	0.018	0.0	0.693	1.000	-	-	-	-	-	-	-	-
esophageal squamous cell carcinoma	1.338	(0.965, 1.854)	0.081	62.8	0.068	1.000	0.731	-	-	-	-	-	-	-
hepatocellular carcinoma	1.364	(0.989, 1.881)	0.059	56.8	0.128	1.000	-	1.315	(1.033, 1.674)	0.026	52.4	0.098	1.000	0.886
gastric cancer	1.990	(1.540, 2.573)	<0.001	28.4	0.247	1.000	0.432	2.063	(1.582, 2.691)	<0.001	0.0	0.834	0.296	0.093
colonrectal cancer	1.961	(1.468, 2.619)	<0.001	32.5	0.227	1.000	0.393	-	-	-	-	-	-	-
country
China	1.926	(1.547, 2.399)	<0.001	0.0	0.476	1.000	0.724	1.493	(1.180, 1.889)	0.001	60.2	0.028	1.000	0.551
Japan	1.443	(1.002, 2.078)	0.049	65.6	0.013	1.000	0.601	1.986	(1.453, 2.714)	<0.001	0.0	0.609	0.296	0.209
protein/mRNA
protein	1.488	(1.194, 1.854)	<0.001	46.1	0.054	0.858	0.929	1.500	(1.247, 1.805)	<0.001	52.7	0.031	0.754	0.240
mRNA	2.013	(1.563, 2.592)	<0.001	0.0	0.392	0.734	0.345	1.630	(0.924, 2.875)	0.092	52.9	0.145	1.000	-
quality assessment
score >=15	1.693	(1.290, 2.222)	<0.001	50.1	0.062	0.764	0.418	1.472	(1.142, 1.898)	0.003	66.7	0.017	0.806	0.693
score <15	1.586	(1.196, 2.104)	0.001	48.8	0.069	1.000	0.966	1.668	(1.246, 2.234)	0.001	39.7	0.156	0.806	0.023
sample size
large (>=100)	1.702	(1.394, 2.078)	<0.001	43.8	0.059	0.640	0.535	1.478	(1.194, 1.829)	<0.001	62.5	0.014	0.548	0.391
small (<100)	1.397	(0.820, 2.379)	0.218	55.9	0.103	0.296	0.446	1.840	(1.324, 2.555)	<0.001	0.0	0.636	1.000	0.635