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. 2017 Mar 18;8(19):31494–31508. doi: 10.18632/oncotarget.16357

Table 2. Association between FAM13C expression and Ki67-labeling index in all prostate cancers and subsets defined by Gleason score, ERG fusion, and PTEN deletion status.

FAM13C IHC n Ki67 Li (mean) Sth.deviation
all
p < 0.0001
negative 1,991 2.1 0.06
weak 837 2.8 0.09
moderate 1,368 2.9 0.07
strong 1,615 3.6 0.07
pGleason
≤ 3 + 3
p < 0.0001
negative 549 1.7 0.09
weak 158 2.5 0.16
moderate 288 2.5 0.12
strong 298 2.7 0.12
pGleason
3 + 4
p < 0.0001
negative 1,182 2.1 0.07
weak 520 2.8 0.10
moderate 801 2.9 0.08
strong 887 3.4 0.08
pGleason
4 + 3
p < 0.0001
negative 198 2.7 0.25
weak 121 2.9 0.32
moderate 219 3.6 0.24
strong 311 4.2 0.20
pGleason
≥ 4 + 4
p = 0.0143
negative 53 3.4 0.60
weak 34 3.6 0.75
moderate 52 4.4 0.61
strong 109 5.5 0.42
PTEN normal
p < 0.0001
negative 955 2.5 0.09
weak 453 3.0 0.13
moderate 711 3.1 0.10
strong 902 3.6 0.09
PTEN deleted
p = 0.0002
negative 69 2.9 0.35
weak 76 3.3 0.34
moderate 187 3.3 0.21
strong 328 4.2 0.16
ERG negative
p < 0.0001
negative 1,537 1.9 0.07
weak 464 3.0 0.13
moderate 589 3.2 0.11
strong 531 3.9 0.12
ERG positive
p < 0.0001
negative 424 2.5 0.12
weak 357 2.6 0.13
moderate 747 2.8 0.09
strong 1,060 3.4 0.08