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. 2017 Feb 24;8(19):31509–31520. doi: 10.18632/oncotarget.15663

Table 4. Univariate and multivariate analyses of the prognostic influence of clinicopathological factors on overall survival.

Clinicopathological features median OS (month) Univariate analyses Multivariate analyses
OS (%) χ2 P HR 95.0% CI for HR P
1year 3year 5year low high
ECOG performance status
(0,1) 72.00 90.80 65.52 24.14 0.019 0.891
(2,3) 72.00 95.24 64.28 35.71
Age (y)
<50 72.00 94.55 69.09 29.09 2.375 0.123
≥50 70.89 90.54 62.16 27.03
Stage
II 72.00 96.72 68.85 26.23 3.210 0.073
III 72.00 88.24 61.76 29.41
Lymph nodes metastases
No 72.00 100.00 85.71 48.57 31.257 0.000 0.869 0.411 1.835 0.712
Yes 32.77 84.75 40.68 3.39
Differentiation
Well-moderate 72.00 93.55 58.06 25.81 0.028 0.867
Poor 72.00 91.04 71.64 29.85
Tumor size
≥5.7cm 53.24 87.95 48.19 16.87 23.076 0.000 2.646 0.987 7.092 0.053
<5.7cm 72.00 100.00 95.65 47.83
SCC-ag level (ng/ml)
<2 70.99 97.92 62.50 31.25 1.101 0.577
2-10 72.00 84.91 66.04 24.53
>10 72.00 96.43 67.86 28.57
Hb level (g/dl)
<10 72.00 91.49 71.28 29.79 6.466 0.004 0.704 0.389 1.276 0.247
≥10 48.95 94.29 48.57 22.86
Treatment
Radiation 72.00 90.54 62.16 22.97 0.009 0.925
Concurrent Chemoradiation 72.00 94.55 69.09 34.55
AURKA IHC
High 38.44 86.30 42.47 5.48 44.402 0.000 9.091 2.597 32.258 0.001
Low 72.00 100.00 94.64 57.14