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. 2017 Mar 29;8(19):32068–32082. doi: 10.18632/oncotarget.16643

Figure 1. Effect of T0901317 on the expression of LXRα and LXRβ and their target genes ABCA1 and ABCG1 in mouse retina.

Figure 1

mRNA levels were measured at P14. (A, B) LXRα and LXRβ expression levels in C57 and rd1 mice. The LXRα mRNA expression level is decreased by T0 treatment in rd1 mice, whereas there is no significant difference between T0 treated and non-treated C57 mice. LXRβ mRNA expression levels is increased by T0 treatment in both groups of mice. (C, D) ABCA1 and ABCG1 expression levels in C57 and rd1 mice. Both genes levels are increased by T0 treatment compared with vehicle treatment. n=4 in each group. ***P<0.001, **P<0.01, *P<0.05.