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. 2017 Mar 29;8(19):32068–32082. doi: 10.18632/oncotarget.16643

Figure 3. T0 treatment decreases the overexpression of GFAP in rd1 mice.

Figure 3

(A-H) Representative images of GFAP expression in C57 and rd1 mice pretreated with T0 or vehicle. (E-H) Images are higher-power views of the boxed areas in A-D. (I) Quantitative analysis of the density of GFAP expression in the higher-power fields of each group in E-H. (J) Representative western blot of retina lysates from C57 and rd1 mice pretreated with T0 or vehicle. (K) The retina from rd1 mice shows significantly more GFAP/GAPDH than that from C57 mice, while T0 treatment significantly reduces this level. RGCL, retinal ganglion cell layer; IPL, inner plexiform layer; INL, inner nuclear layer; OPL, outer plexiform layer; ONL, outer nuclear layer. Data are presented as the mean ± SEM. n=5 mice per group. **P< 0.01. Scale bar in H=75 μm and applies to (E-H).