Table 4. Overall analysis of complications comparing RARP and RRP.
Outcome of interest | No. of studies | No.of patients RARP/RRP |
OR (95%CI) | p-value | Study heterogeneity | |||
---|---|---|---|---|---|---|---|---|
Chi2 | df | I2 | p-value | |||||
Overall complications | 25 | 43087/28834 | 0.43 [0.32, 0.58] | <0.001 | 499.59 | 24 | 95% | <0.001 |
Rectal injury | 8 | 3888/8110 | 0.16[0.07, 0.39] | <0.001 | 5.22 | 7 | 0% | 0.63 |
Pulmonary embolism | 9 | 37575/24635 | 0.47[0.37, 0.59] | <0.001 | 5.04 | 8 | 0% | 0.75 |
Wound infections | 10 | 11161/10587 | 0.23[0.11, 0.46] | <0.001 | 31.49 | 9 | 71% | <0.001 |
Bladder neck contracture | 4 | 1993/2409 | 0.21[0.08,0.60] | 0.003 | 8.39 | 3 | 64% | 0.04 |
UTI | 4 | 6586/2546 | 0.75[0.37,1.54] | 0.44 | 15.35 | 3 | 80% | 0.002 |
Urinary retention | 3 | 2042/960 | 0.63[0.47,0.84] | 0.002 | 2.44 | 2 | 18% | 0.29 |
Obturator nerve injury | 2 | 1453/585 | 0.09[0.01,0.75] | 0.03 | 0.01 | 1 | 0% | 0.91 |
DVT | 7 | 7479/3072 | 0.40[0.25,0.66] | <0.001 | 10.82 | 6 | 45% | 0.09 |
Urinary leakage | 8 | 30940/15631 | 0.64[0.58,0.70] | <0.001 | 8.87 | 7 | 21% | 0.26 |
ileus | 8 | 3412/8501 | 0.92[0.56,1.51] | 0.73 | 2.20 | 7 | 0% | 0.95 |
lymphocele | 9 | 45258/2639 | 0.52[0.29,0.94] | 0.03 | 8.93 | 8 | 10% | 0.35 |
Urinary continence-3mo | 9 | 997/941 | 1.54[0.92,2.58] | 0.10 | 22.06 | 8 | 64% | 0.005 |
Urinary continence-12mo | 9 | 1565/2179 | 1.03[0.84,1.27] | 0.75 | 17.41 | 8 | 54% | 0.03 |
Potent recovery-3mo | 5 | 1169/820 | 3.19[1.19,8.56] | 0.02 | 51.94 | 4 | 92% | <0.001 |
Potent recovery-12mo | 7 | 1395/1574 | 2.37[1.30,4.33] | 0.005 | 55.43 | 6 | 89% | <0.001 |
Readmission rate | 7 | 11632/7060 | 0.83[0.74,0.94] | 0.002 | 36.82 | 6 | 84% | <0.001 |
RARP=robot-assisted radical prostatectomy; RRP= retropubic radical prostatectomy; OR = odds ratio; WMD = weighted mean difference; CI = confidence interval; UTI=urinary tract infection; DVT=deep venous thrombosis.