Table 1.
Baseline Characteristics
| DCM (N=14447) | RCM (N=823) | ICM (N=11799) | HCM (N=602) | Valvular (N=584) | CHD (N=964) | Other (N=1528) | |
|---|---|---|---|---|---|---|---|
|
| |||||||
| Females | 4562 (32) | 291 (35) | 1556 (13) | 231 (38) | 208 (36) | 385 (40) | 535 (35) |
|
| |||||||
| Age, (yrs) | 49+/−13 | 53+/−12 | 58+/−8 | 46+/−14 | 54+/−11 | 36+/−12 | 45+/−15 |
|
| |||||||
| Race | |||||||
| White | 8190 (57) | 600 (73) | 9380 (80) | 489 (81) | 396 (68) | 795 (82) | 1101 (72) |
| Black | 4461 (31) | 166 (20) | 1210 (10) | 52 (9) | 105 (18) | 82 (9) | 247 (16) |
| Hispanic | 1260 (9) | 36 (4) | 757 (6) | 35 (6) | 51 (9) | 55 (6) | 125 (8) |
| Other | 536 (4) | 21 (3) | 452 (4) | 26 (4) | 32 (5) | 32 (3) | 55 (4) |
|
| |||||||
| Insurance | |||||||
| Private | 7658 (53) | 590 (72) | 5994 (51) | 411 (68) | 327 (56) | 584 (61) | 877 (57) |
| Medicare | 3826 (26) | 157 (19) | 4142 (35) | 110 (18) | 170 (29) | 152 (16) | 400 (26) |
| Medicaid | 2106 (15) | 40 (5) | 1028 (9) | 56 (9) | 63 (11) | 185 (19) | 188 (12) |
| Other | 857 (6) | 36 (4) | 635 (5) | 25 (4) | 24 (4) | 43 (4) | 63 (4) |
|
| |||||||
| BMI, kg/m2 | |||||||
| 14–19 | 734 (5) | 46 (6) | 266 (2) | 35 (6) | 46 (8) | 138 (14) | 97 (6) |
| 20–24 | 3842 (27) | 262 (32) | 2715 (23) | 179 (30) | 197 (34) | 347 (36) | 465 (30) |
| 25–29 | 4877 (34) | 305 (37) | 4727 (40) | 207 (34) | 233 (40) | 269 (28) | 527 (34) |
| 30–34 | 3457 (24) | 167 (20) | 3100 (26) | 142 (24) | 83 (14) | 163 (17) | 316 (21) |
| 35–40 | 1514 (10) | 43 (5) | 974 (8) | 38 (6) | 25 (4) | 45 (5) | 118 (8) |
|
| |||||||
| UNOS Status | |||||||
| 1A | 3319 (23) | 145 (18) | 2539 (22) | 100 (17) | 115 (20) | 107 (11) | 420 (27) |
| 1B | 6089 (42) | 212 (26) | 4175 (35) | 164 (27) | 198 (34) | 259 (27) | 331 (22) |
| 2 | 4421 (31) | 439 (53) | 4544 (39) | 330 (55) | 258 (44) | 569 (59) | 727 (48) |
| Inactive | 625 (4) | 27 (3) | 541 (5) | * | 13 (2) | 29 (3) | 50 (3) |
|
| |||||||
| ABO blood type | |||||||
| O | 6685 (46) | 349 (42) | 4769 (40) | 270 (45) | 264 (45) | 447 (46) | 678 (44) |
| A | 5073 (35) | 314 (38) | 4963 (42) | 232 (39) | 209 (36) | 367 (38) | 601 (39) |
| B | 2050 (14) | 124 (15) | 1503 (13) | 77 (17) | 81 (14) | 117 (12) | 180 (12) |
| AB | 639 (4) | 36 (4) | 564 (5) | 23 (4) | 30 (5) | 33 (3) | 69 (5) |
|
| |||||||
| Era | |||||||
| Jan1,‘04–Mar31,‘08 | 4729 (33) | 218 (26) | 4431 (38) | 195 (32) | 245 (42) | 339 (35) | 523 (34) |
| Apr1,‘08–Sept3,‘14 | 9718 (67) | 605 (74) | 7368 (62) | 407 (68) | 339 (58) | 625 (65) | 1005 (66) |
|
| |||||||
| Tobacco usage | 5672 (39) | 253 (31) | 7356 (62) | 204 (34) | 226 (39) | 177 (18) | 371 (24) |
|
| |||||||
| Diabetes mellitus | 3274 (23) | 113 (14) | 4518 (38) | 47 (8) | 98 (17) | 67 (7) | 308 (20) |
|
| |||||||
| Hypertension | 5572 (39) | 251 (31) | 5962 (51) | 180 (30) | 203 (35) | 213 (22) | 661 (43) |
|
| |||||||
| Malignancy | 1090 (8) | 109 (13) | 664 (6) | * | 25 (4) | 22 (2) | 128 (8) |
|
| |||||||
| Prior CVA | 655 (5) | 26 (3) | 619 (5) | 29 (5) | 30 (5) | 55 (6) | 66 (4) |
|
| |||||||
| PVD | 218 (2) | 14 (2) | 574 (5) | * | * | 17 (2) | 38 (2) |
|
| |||||||
| Dialysis at listing | 353 (2) | 31 (4) | 305 (3) | 15 (2) | 18 (3) | 17 (2) | 143 (9) |
|
| |||||||
| eGFR, ml/min/1.73m2 | 72+/−30 | 66 +/−28 | 66 +/−26 | 72+/−28 | 65+/−30 | 84+/−35 | 59+/−31 |
|
| |||||||
| Serum albumin, g/dl | 3.6+/−0.7 | 3.8+/−0.7 | 3.7+/−0.7 | 3.9+/−0.7 | 3.8+/−0.7 | 3.9+/−0.8 | 3.6+/−0.7 |
|
| |||||||
| Mean PAP, mm Hg | 30.8 +/−9.7 | 29.7 +/−8.6 | 29.8 +/−10.0 | 30.6 +/−9.7 | 30.6 +/−9.6 | 26.4+/−10.9 | 26.1+/−8.4 |
|
| |||||||
| CI, L/min/m2 | 2.1 +/−0.7 | 2.1 +/−0.6 | 2.2 +/−0.6 | 2.1+/−0.6 | 2.3 +/−0.7 | 2.3 +/−0.7 | 2.2 +/−0.7 |
|
| |||||||
| Pk VO2, ml/kg/min | 12.0 +/−3.5 | 12.0 +/−3.5 | 11.7 +/−3.0 | 11.8 +/−3.5 | 11.3+/−3.3 | 13.0 +/−3.6 | 12.2 +/−4.2 |
|
| |||||||
| Antiarrythmics | 4350 (30) | 182 (22) | 3800 (32) | 176 (29) | 203 (35) | 274 (28) | 259 (17) |
|
| |||||||
| ICD | 11112 (77) | 378 (46) | 8879 (75) | 480 (80) | 405 (69) | 450 (47) | 418 (27) |
|
| |||||||
| Inotropes | 5201 (36) | 210 (26) | 3449 (29) | 157 (26) | 183 (31) | 226 (23) | 407 (27) |
|
| |||||||
| LVAD | 2652 (18) | 31 (4) | 2314 (20) | 22 (4) | 46 (8) | 30 (3) | 63 (4) |
|
| |||||||
| RVAD +/− LVAD Or unspecified | 675 (5) | 16 (2) | 542 (5) | 11 (2) | 25 (4) | 20 (2) | 118 (8) |
|
| |||||||
| TAH or | 69 (<1) | * | 38 (<1) | * | * | * | 16 (1) |
|
| |||||||
| IABP | 670 (5) | 28 (3) | 714 (6) | 12 (2) | 14 (2) | 12 (1) | 94 (6) |
|
| |||||||
| ECMO | 88 (1) | * | 99 (1) | * | * | 17 (18) | 103 (7) |
|
| |||||||
| Ventilator | 316 (2) | 12 (2) | 394 (3) | 10 (2) | 20 (3) | 26 (27) | 150 (10) |
Values are means +/− standard deviations or n (%).
*
Number <10 patients
BMI=body mass index, CHD=congenital heart disease, CI=cardiac index, CVA=cerebral vascular accident, IABP=intra-aortic balloon pump, DCM=dilated cardiomyopathy, eGFR=estimated glomerular filtration rate, ECMO=extracorporeal membrane oxygenation, HCM=hypertrophic cardiomyopathy, ICD=implantable cardioverter defibrillator, ICM=ischemic cardiomyopathy, LVAD=left ventricular assist device, PAP=pulmonary artery pressure, Pk VO2 peak oxygen consumption, PVD= peripheral vascular disease, RCM=restrictive cardiomyopathy, RVAD=right ventricular assist device, TAH=total artificial heart, UNOS= United Network for Organ Sharing