Table 4.

The AUC With 95% Confidence Intervals for BA_EC Adjusted for Age and Sex for Different Relative Weight of CA, ε (Compared With the Weights of Biomarkers)

$\epsilon =\frac{w_{\text{CA}}}{{{\displaystyle \sum }}_{j=1}^m{w}_{j } }$	$s_{\text{BA}}^2$	Age + Sex + BAEC		Sex + BAEC
		AUC	95% Confidence Interval	AUC	95% Confidence Interval
0	Infinity	0.726	0.695–0.757	0.679	0.646–0.712
0.05	3,500	0.726	0.695–0.757	0.681	0.646–0.712
0.1	1,750	0.726	0.695–0.757	0.684	0.651–0.716
0.2	900	0.726	0.695–0.757	0.688	0.659–0.720
0.5	350	0.726	0.695–0.757	0.699	0.667–0.731
1.0	175	0.726	0.695–0.757	0.713	0.690–0.707
10.0	17	0.726	0.695–0.757	0.716	0.691–0.708

Notes: AUC = area under the receiving-operating characteristic; BA = biological age; CA = chronological age. When the variance $s_{\text{BA}}^2$ increases, its ability to accurately predict mortality decreases.