. 2017 Mar 7;157(2):342–353. doi: 10.1093/toxsci/kfx049

TABLE 1.

Spatiotemporal Effects of DFP Intoxication on ADC Distribution Characteristics

Brain Region	DPE	Mean	10th percentile	90th percentile	SD
	3	NS	NS	↑^***	↑^***
	7	↑^*	NS	↑^**	↑^*
Hippocampus	14	↑^**	NS	↑^***	↑^*
	21	↑^***	↑^***	↑^**	NS
	28	↑^***	↑^***	↑^***	↑^***
	3	NS	↓^*	↑^**	↑^***
	7	NS	NS	↑^*	↑^*
Piriform Cortex	14	↑^**	↑^*	↑^***	NS
	21	↑^**	↑^*	↑^**	↑^**
	28	↑^*	NS	↑^***	NS
	3	↓^***	↓^***	NS	↑^***
	7	NS	NS	NS	↑^**
Thalamus	14	NS	NS	↑^***	↑^*
	21	↑^***	↑^**	↑^***	↑^***
	28	NS	NS	↑^***	↑^***

Abbreviations: NS, not significant; ADC, apparent diffusion coefficient; SD, Standard Deviation.

Statistical significance was calculated using a repeated measures regression model comparing DFP-intoxicated animals to vehicle controls: ↑, DFP group > vehicle group; ↓, DFP group < vehicle group.

P < 0.05

^**

P < 0.01

^***

P < 0.001