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Comparison of IC50 values for free doxorubicin and doxorubicin co-delivered with polyhedral oligomeric silsesquioxane in three different cell lines.
| Sample | IC50 [µM/L] | ||
|---|---|---|---|
| MCF-7 | HeLa | HMEC-1 | |
| Doxorubicin (DOX) | 17.44 ± 5.23 | 1.45 ± 0.15 | 10.33 ±4.63 |
| POSS:DOX 1:1 | 13.65 ± 4.03 | 1.44 ± 0.12 | 10.92 ± 2.26 |
| POSS:DOX 1:2 | 76.97 ± 35.11 | 1.61 ± 0.26 | 14.81 ± 12.10 |
| POSS:DOX 1:4 | 109.10 ± 55.88 | 1.25 ± 0.08 | 9.11 ± 4.56 |
| POSS:DOX 1:8 | 2.69 ± 0.15 | 0.92 ± 0.09 | 2.51 ± 0.42 |
