. Author manuscript; available in PMC: 2018 Jun 1.

Published in final edited form as: J Neurovirol. 2017 Jan 20;23(3):404–421. doi: 10.1007/s13365-016-0510-z

Table 2.

Summary of Gisslén, Frascati, and DSM-5 criteria for HIV- associated neurocognitive disorder

	DSM-5	Frascati	Gisslén
Domain Threshold for Mild Impairment	Score greater than 1, but less than 2 SD below the mean	Score ≥ 1 SD below on 2 tests, or ≥ 1.5 below on 1 test	Doman T-score > 1.5 SD below the mean
Domain Threshold for Major Impairment	Score greater than 2 SD below the mean	Score ≥ 2 SD below on 2 tests, or ≥ 2.5 below on 1 test	Domain T-score > 2 SD below mean
Minimum Number of Impaired Domains	≥1	≥2	≥2
Cognitive Domains Considered
Attention	✔	✔	✔
Executive Function	✔	✔	✔
Learning and Memory	✔	✔	✔
Language	✔
Speed of Processing	✔^*	✔	✔
Motor	✔^**	✔	✔
Perceptual-Motor	✔
Functional Domains Used in the Current Study
ADLs (IADLs & BADLs)	✔	✔	✔
Employment status		✔	✔
POMS (Confusion and Bewilderment)	✔	✔	✔
Karnofsky		✔	✔

Note.

For DSM-5 criteria, Speed of Processing is subsumed within the Attention domain.

^**

For DSM-5 criteria, Motor is subsumed within the Perceptual-Motor domain.