Table 3.
Neuropsychological Domains & Measures | HIV− (n = 196) | HIV + (n = 353) | p | Cohen’s d | Demographics Adjusted |
---|---|---|---|---|---|
Attention Domain | |||||
Digit Span | 53.67 (9.3) | 50.22 (9.3) | < .0001 | 0.37 | Age |
CVLT-II Trial 1 | 49.20 (13.4) | 44.9 (11.8) | .0001 | 0.34 | Sex, Age |
Executive Domain | |||||
Tower of London Moves | 48.54 (10.8) | 49.12 (11.7) | .567 | −0.05 | Age |
Actions* | 47.26 (9.5) | 45.79 (9.3) | .076 | 0.16 | Ed. |
Trail Making Test Part B | 51.08 (10.8) | 49.66 (11.8) | .163 | 0.13 | Race, Sex, Age, Ed. |
Learning Domain | |||||
CVLT-II Trial 1–5 | 54.96 (11.5) | 50.78 (10.7) | <.0001 | 0.38 | Sex, Age |
LM1 Total | 55.65 (11.4) | 51.10 (10.8) | <.0001 | 0.41 | Age |
Memory Domain | |||||
LM2 Total | 57.61 (11.1) | 52.39 (11) | <.0001 | 0.47 | Age |
CVLT-II Long Delay Free Recall | 52.04 (10.7) | 48.13 (11.8) | .0001 | 0.35 | Sex, Age |
Speed of Processing Domain | |||||
Tower of London Execution Time | 47.58 (9.6) | 46.89 (10) | .427 | 0.07 | Age |
Trail Making Test Part A | 51.77 (10) | 50.23 (10.7) | .093 | 0.15 | Race, Sex, Age, Ed. |
Motor Domain | |||||
Grooved Peg Board (Dom) | 48.77 (10.3) | 47.42 (10.8) | .156 | 0.13 | Race, Sex, Age, Ed. |
Grooved Peg Board (Non Dom) | 48.71 (11.2) | 47.35 (10.6) | .160 | 0.13 | Race, Sex, Age, Ed. |
Language Domain** | |||||
Boston Naming Test | 49.54 (12.5) | 49.63 (12) | .930 | −0.01 | Age, Ed. |
Note. Data are presented as mean T-scores (standard deviation) for each study group. Digit Span subtest from Wechsler Memory Scale, 3rd edition; CVLT-II = California Verbal Learning Test, 2nd edition; LM 1 & 2 = with Logical Memory I subtest from the WMS-III.
Actions were included within the executive domain for only Frascati and Gisslén neurocognitive criteria.
The Language domain was included only in the DSM-5 criteria comprised of the Boston Naming Test and Actions.