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. Author manuscript; available in PMC: 2017 Jun 5.
Published in final edited form as: J Neurol Neurosci. 2017 Feb 28;8(1):176. doi: 10.21767/2171-6625.1000176

Table 2.

ADAS- Cog (11) Improvement (SEM).

Delayed Word Recall Pre=0.77 (0.43) Post = 1.6 (0.37) p=0.10
TX Group mean PRE-test (0.5 score) was lower than Controls pre-test mean score (1.333), but at POST testing the TX Group Mean rose to 1.83 and Ctrl Grp mean post-test score remained at 1.333.
Trail Making A Pre=3.55 (1.73) Post 1.33 (0.87) p=0.044
Omission Errors - More active and successful engagement with the task.
Ideational Praxis Pre= 3.55 (0.38) Post= 4.33 (0.33) p=0.03
Multi step instructions to address and seal envelope.
Boston Naming Pre=11.75 (2.91) Post 13.00 (2.43) p=0.035
Recall names of familiar objects when shown them on cards.
Worsened
Auditory Verbal Learning Pretest 2.44 (0.53) Post 1.66 (0.58) p=0.08
Auditory Verbal Learning Test Trial 1
(first exposure to auditory word list- immediate verbal memory)
Pre-Test mean TX = 3.00 (0.67) and CTRL Pre-Test mean = 1.33 (1.53)
Post-Test mean TX= 2.167 (0.60) and CTRL Post-Test mean = .667 (0.67)
Trail Making-A Pretest 2.00 (1.64) Post Test 2.88 (1.81) p=.034
Commission Errors = More attempts = > effort = > potential errors.
Cortical Perfusion
ARVI* (Treatment): 1.77%
BSMN (Treatment): 6.86%
EGKY (Treatment): 4.93%
MCLN (Treatment) : 2.72%
EHUL (Control): −0.19%
HJLK (Control): 0.86%
LDMC (Control): 3.32%**
*

Study subject identifier codes

**

This placebo group subject came to study having had not left her small town urban row home where she lived with her husband and over the previous 18months had not been outside except for doctor appointments. Her response was clearly tied to the intensive positive interpersonal stimulation of the treatment context.