Table 1. Results of multiple comparisons across relevant surrogates tested.
Wilcoxon p-values for Steady-State Modulus | Human | Mouse | Chicken | Agarose | Gelatin | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Menina | Tumor | Brain | Liver | Crassus | Tenuis | Breast | 0.2% | 0.4% | 0.6% | Knox® | ||
Human | Menina | 0.0168 | 0.0006 | 0.0043 | 0.0969 | 0.0043 | 0.0073 | 0.7191 | 0.0005 | <0.0001 | 0.0192 | |
Mouse | Tumor | 0.0168 | 0.0030 | 0.0372 | 0.1427 | 0.0253 | 0.0372 | 0.0048 | 0.8383 | 0.0024 | 0.8170 | |
Brain | 0.0006 | 0.0030 | 0.4727 | 0.0050 | 0.0050 | 0.0050 | 0.0004 | 0.0001 | <0.0001 | 0.0050 | ||
Chicken | Liver | 0.0043 | 0.0372 | 0.4727 | 0.0304 | 0.0304 | 0.0304 | 0.0058 | 0.0058 | 0.0032 | 0.0304 | |
Crassus | 0.0969 | 0.1427 | 0.0050 | 0.0304 | 0.0304 | 0.0304 | 0.0058 | 0.0196 | 0.0032 | 0.0304 | ||
Tenuis | 0.0043 | 0.0253 | 0.0050 | 0.0304 | 0.0304 | 0.6650 | 0.0058 | 0.0133 | 0.7263 | 0.0606 | ||
Breast | 0.0073 | 0.0372 | 0.0050 | 0.0304 | 0.0304 | 0.6650 | 0.0058 | 0.0058 | 0.9601 | 0.0304 | ||
Agarose | 0.2% | 0.7191 | 0.0048 | 0.0004 | 0.0058 | 0.0058 | 0.0058 | 0.0058 | 0.0002 | <0.001 | 0.0058 | |
0.4% | 0.0005 | 0.8383 | 0.0001 | 0.0058 | 0.0196 | 0.0133 | 0.0058 | 0.0002 | <0.001 | 0.9436 | ||
0.6% | <0.0001 | 0.0024 | <0.0001 | 0.0032 | 0.0032 | 0.7263 | 0.9601 | <0.001 | <0.001 | 0.0032 | ||
Gelatin | Knox® | 0.0192 | 0.8170 | 0.0050 | 0.0304 | 0.0304 | 0.0606 | 0.0304 | 0.0058 | 0.9436 | 0.0032 |
P-values were obtained by performing a non-parametric Wilcoxon test for multiple comparisons in JMP software (SAS).
Grey boxes indicate tissues/surrogates that are not statistically different (p > 0.05), and values in bold indicate potential surrogates for normal brain and brain tumors in quasi-static in vitro applications.
aMenin = human meningioma