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Serum levels of alanine aminotransferase (ALT) and aspartate aminotransferase (AST).
| Sham | 3.0 h I/R | 6.0 h I/R | 6.0 h I/R+endothelin-1 | |
| ALT (U/L) | 50.2 (16.6) | 197.0 (40.4) * | 226.2 (38.5) * | 261.6 (37.8) *## |
| AST (U/L) | 177 (34) | 1825 (410) *# | 2551 (616) * | 2856 (320) *## |
Data expressed as Mean (SD); n = 7 for each group; * p < 0.001 vs. sham; # p < 0.02 vs. 6.0 h I/R; ## p < 0.01 vs. 3.0 h I/R.
