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. 2017 Jun 5;12(6):e0178764. doi: 10.1371/journal.pone.0178764

Table 3. Volume and cost of insulins by class-duration of action and molecular origin in Poland.

Number of DDDs in thousands. Costs in USD x 1000.

Insulin type 2012 2013 2014 2015
Biphasic/human Volume; DDD (%) 73,313 (36.43) 78,975 (34.91) 79,200 (33.1) 76,950 (31.41)
Cost; USD (%) 114,835 (32.19) 122,291 (30.36) 120,801 (28.54 117,125 (26.82)
Biphasic/analogue Volume; DDD (%) 12,525 (6.22) 13,200 (5,83) 13,613 (5.69) 13,125 (5.36)
Cost; USD (%) 25,593 (7.17) 26,743 (6.64) 27,359 (6.44) 26,389 (6.04)
Short/human Volume; DDD (%) 23,325 (11.59) 26,100 (11.54) 21,038 (8.79) 21,750 (8.88)
Cost; USD (%) 36,451 (10.22) 40,364 (10.02) 41,448 (9.76) 43,131 (9.88)
Short/analogue Volume; DDD (%) 59,175 (29.40) 67,650 (29.90) 73,013 (30.51) 76,800 (31.35
Cost; USD (%) 122,654 (34.39) 138,715 (34.44) 148,228 (34.91) 155,659 (35.65)
Long/human Volume; DDD (%) 30,375 (15.09) 34,725 (15.35) 44,100 (18.43) 46,463 (18.97)
Cost; USD (%) 47,576 (13.34) 53,855 (13.37) 56,251 (13.25) 59,068 (13.53)
Long/analogue Volume; DDD (%) 2,550 (1.27) 5,588 (2.47) 8,325 (3.48) 9,900 (4.04)
Cost; USD (%) 9,598 (2.69) 20,851 (5.18) 30,515 (7.19) 35,273 (8.08)
Total Volume; DDD (%) 201,263 (100.00) 226,238 (100.00) 239,288 (100.00) 244,988 (100.00)
Cost; USD (%) 356,707 (100) 402,819 (100) 424,599 (100) 436,645 (100)

DDD: definded daily dose; USD: United States Dollar