Table IV.
All patients (n = 113)
|
Subgroup analysis with BM graft (n = 79)
|
|||||||
---|---|---|---|---|---|---|---|---|
Variable | Cumulative incidence (95% CI)
|
HR; 95% CI | P-value | Cumulative incidence (95% CI)
|
HR; 95% CI | P-value | ||
Conventional GVHD prophylaxis (n = 72) | PTCy (n = 41) | Conventional GVHD prophylaxis (n = 45) | PTCy (n =34) | |||||
NRM, 2 years, | 25% (16–38) | 35% (23–54) | 1.4; 0.7–2.8 | 0.3 | 1.6 (0.6–3.8) | 0.3 | ||
Progression, 2 years | 31% (22–44) | 20% (22–37) | 0.6; 0.3–1.4 | 0.2 | 0.6 (0.3–1.5) | 0.3 | ||
PFS, 2 years | 38% (27–50) | 42% (27–57) | 0.9; 0.5–1.5 | 0.7 | 43% (28–58) | 56% (37–72) | 0.9 (0.5–1.6) | 0.8 |
OS, 2 years | 40% (28–52) | 52% (35–67) | 0.8; 0.5–1.4 | 0.5 | 38% (24–52) | 44% (27–60) | 0.8 (0.4–1.6) | 0.5 |
BM, bone marrow; CI, Confidence Interval; HR, Hazard Ratio; GVHD, graft-versus-host disease; PTCy, Post-transplant cyclophosphamide; NRM, non-relapse mortality; PFS, progression-free survival; OS, overall survival.