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. 2017 Jun 5;12(6):e0178925. doi: 10.1371/journal.pone.0178925

Fig 5. Cyclin E, PCNA and Cdk2 colocalize with p21 in the nucleolus in HCT116 cells after DNA damage.

Fig 5

A) Immunostaining of endogenous p21 and CycE, PCNA or Cdk2 in HCT116 cells treated with Adr for 48 hours. B) Immunostaining of p21 and PCNA, CycE or Cdk2 HCT116 cells transfected with non-targeted (siNT), p21 (sip21) or UBC9 (siUBC9) siRNAs and treated with Adr for 48 hours. C) Immunostaining of PCNA, CycE or Cdk2 in HCT116 p21KO cells treated with Adr for 48 hours. Ph.C.: Phase contrast. Scale bar: 5μm.