TABLE 2.
DONOR DEMOGRAPHICS OF NONASTHMATIC PHAEC CULTURES USED FOR EPITHELIAL GENE EXPRESSION ARRAY
Donor | Sex | Age (yr) | Sample Type* | Cause of Death |
---|---|---|---|---|
N1 | M | 20 | Donor lung | Head trauma |
N2 | F | 20 | Donor lung | Head trauma |
N3 | M | 21 | NHBEs (Lonza, Basel, Switzerland) | |
N4 | F | 23 | Bronchial brushing | |
N5 | M | 47 | Donor lung | Head trauma |
Definition of abbreviations: F, female; M, male; N, nonasthmatic; NHBEs, normal human bronchial epithelial cells; PHAEC, primary human airway epithelial cell.
Airway epithelial cells were obtained from the upper airways of human lungs deemed unsuitable for transplantation, from bronchial brushing or commercially available NHBEs. All donors lacked doctor-diagnosed asthma.