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. 2013 Dec;49(6):1029–1037. doi: 10.1165/rcmb.2012-0462OC

Figure 2.

Figure 2.

ATLa treatment ameliorates markers of tissue repair. Lungs were removed from animals on Days 14 and 21 after treatment with saline, BLM (0.06 U/mouse), BLM plus ATLa late treatment (1 μg/mouse and boosted 0.1 μg/mouse on Days 7 and 10, respectively), or BLM plus BOC-2 with ATLa (100 μg/mouse and 10 μg/mouse of BOC-2 on Days 7 and 10). Immunolabeling for collagen 1 (AC), TGF-β (DG), SP-C (HL, Day 14), and SP-C on Day 21 (KO) and vascular endothelial growth factor (PR) as described in Materials and Methods (n = 6 for each experimental group). Pictures are representative of each group. *P < 0.05 compared with saline group; #P < 0.05 compared with BLM group.