Table 3.

The influence of Pro and Raz on primary and metastatic tumor of LLC: PTI (%) – Primary tumor inhibition. MFCPM – metastatic foci count per mouse. Route: ip × 7 every 2 days. Experiment term was 20 days, * P < 0.001(treatment vs vehicle control). The numbers of mice were 30 for both control group and each treatment group. 100 % survival was observed in each group.

Compounds	Dosage mg/kg/d	Body weigh (g)	PTI(%)	MFCPM
Control	---	22.8/21.4	--	30.9 ± 7.3
Razoxane	20	22.7/21.5	40.3	1.2 ± 0.5*
Probimane	30	23.3/22.5	42.0	1.5 ± 0.5*
Probimane	60	23.3/20.3	48.0	1.0 ± 0.2*