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. Author manuscript; available in PMC: 2017 Jun 5.
Published in final edited form as: Clin Sci (Lond). 2017 Feb 1;131(3):181–195. doi: 10.1042/CS20160378

Figure 4. LNP.

Figure 4

Schematic representation of a LNP made up of cationic lipids that covalently bind with the nucleic acid content, e.g. miRNA or ASO, phospholipids that provide structure to the lipid bilayer, cholesterol that provides stability of the lipid bilayer, and lipid-anchored PEG that limits aggregation and non-specific uptake.