. 2017 Jun 5;12(6):e0178839. doi: 10.1371/journal.pone.0178839

Table 4. Associations between genetic markers and POP in top regions identified from admixture mapping.

Classification	SNP	Region	BP	SNP OR (95% CI)	P	EA/RA	EAF	EAF- YRI/ASW/CEU
Grade 0 vs. 2/3	rs4777810	15q26.2	93825164	0.37 (0.23, 0.50) ^a	5.58x10^-5	G/A	0.19	0.03/0.17/0.57
Grade 0 vs. 2/3
Grade 0 vs. 1–3	rs78992478	1q42.1–42.3	235397083	3.15 (1.93, 5.14) ^b	4.23x10^-6	C/T	0.92	0.98/0.94/1.00
Grade 0 vs. 1–3	rs2501094	1q42.1–42.3	225095329	1.63 (1.32, 1.64) ^b	5.47x10^-6	C/A	0.55	0.50/0.63/0.99

SNP: Single Nucleotide Polymorphism; BP: Base Pair; P: P-value; OR: Odds Ratio; CI: Confidence Interval; EA: Effect Allele; RA: Reference Allele; EAF: Effect Allele Frequency.

a Modeled against SNP, adjusted for covariates (age at ascertainment, BMI, parity and continuous axes of MDS components).

b Modeled against SNP, adjusted for covariates (age at ascertainment, BMI, parity and continuous axes of MDS components).