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(A) The singly-bound head is circled with red dashed line. Panels (B) and (C) follow the same labeling and formatting as in Figure 4. (B) The singly bound head adopts a closed conformation of the nucleotide cleft. (C) There is continuous density between helix α6 and the microtubule surface and no density overlaps with the neck linker strand in 4HNA fit into the map.
