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. Author manuscript; available in PMC: 2017 Jun 5.
Published in final edited form as: Circulation. 2016 Nov 14;135(6):566–577. doi: 10.1161/CIRCULATIONAHA.116.023266

Figure 1. Freedom from Major Adverse Cardiovascular Events According to Sex (Panels A, B), Sex and Angiographic Disease (Panels C, D), or Sex and Coronary Flow Reserve (Panels E, F).

Figure 1

Compared to men, women experienced similar if not greater risk of cardiovascular events (Panels A, B). In men but not women, outcomes associated with presence or absence of severely obstructive CAD (Panels C, D). Not all women, but only those with impaired CFR, demonstrated the highest risk of CVD events (Panels E, F). CADPI, CAD prognostic index; CFR, coronary flow reserve.

*Adjusted for nonwhite race; pretest clinical score; history of PCI, hypertension, and insulin use; BMI >27 kg/m2; LVEF <50%; and LV ischemia >10%

†Adjusted for nonwhite race; pretest clinical score; history of PCI, hypertension, and insulin use; BMI >27 kg/m2; LVEF <50%; LV ischemia >10%; and time-dependent revascularization with PCI or CABG within 90d of noninvasive imaging

‡Adjusted for nonwhite race; pretest clinical score; history of PCI, hypertension, and insulin use; BMI >27 kg/m2; LVEF <50%; LV ischemia >10%; CAD prognostic index; time-dependent revascularization with PCI or CABG within 90d of noninvasive imaging