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. Author manuscript; available in PMC: 2018 Jun 15.
Published in final edited form as: Cancer. 2017 Apr 24;123(12):2312–2319. doi: 10.1002/cncr.30687

Table 1.

Summary measures for natural history events occurring within a man’s lifetime, up to age 85 years, projected by the three models. Ratios are for black men relative to all races and are calculated using 4 significant digits for all measures.

Measure FHCRC MISCAN UMICH

Black men All races Ratio Black men All races Ratio Black men All races Ratio
Risk of onset, % 43 28 1.56 30 24 1.28 37 29 1.29
Risk of clinical diagnosis, % 15 9 1.70 13 10 1.33 18 13 1.44
Risk of metastatic clinical diagnosis, % 4 2 2.53 4 2 1.84 4 2 2.26
Risk of clinical diagnosis given onset, % 35 32 1.09 45 43 1.04 49 44 1.12
Risk of metastatic clinical diagnosis given onset, % 9 6 1.63 13 9 1.44 12 7 1.75
Mean age at onset, y 57 59 0.97 64 67 0.96 65 66 0.99
Mean age at clinical diagnosis, y 71 72 0.99 70 72 0.98 75 76 0.98
Mean age at metastatic clinical diagnosis, y 70 72 0.98 71 73 0.98 74 74 0.99
Mean time from onset to clinical diagnosis, y 18 18 1.02 10 10 0.98 17 18 0.92
Mean time from onset to metastatic clinical diagnosis, y 16 15 1.03 12 13 0.94 16 21 0.79
Risk of PSA or clinical diagnosis*, % 16 10 1.65 20 16 1.23 20 14 1.45
Risk of PSA or clinical diagnosis given onset*, % 38 36 1.06 66 68 0.97 53 47 1.12
Mean age at PSA or clinical diagnosis*, y 70 71 0.99 69 71 0.98 73 74 0.98
Mean time from PSA to clinical diagnosis*, y 7 7 1.03 8 9 0.95 7 7 0.96
*

These measures are in the presence of modeled PSA screening patterns in 1987–2000 and are included for reference.