. Author manuscript; available in PMC: 2018 Jul 1.

Published in final edited form as: Calcif Tissue Int. 2017 Feb 28;101(1):75–81. doi: 10.1007/s00223-017-0257-4

Table 2.

Femoral bone trabecular and cortical architecture

	VEH	ZOL	ZOL + RAL-L	ZOL + RAL-H	ANOVA P value
Trabecular BV/TV (%)	21.6 ± 4.0	29.7 ± 4.0 ^*	35.9 ± 6.3 ^*^#	36.1 ± 4.9 ^*^#	0.0001
Trabecular thickness (μm)	77 ± 8	82 ± 9	93 ± 8 ^*^#	91 ± 8 ^*^#	0.0001
Trabecular number (^#/mm)	2.8 ± 0.3	3.6 ± 0.3^*	3.8 ± 0.4^*^#	3.9 ± 0.3^*^#	0.0001
Total cross sectional area (mm²)	2.0 ± 0.2	2.2 ± 0.3	2.2 ± 0.4	2.0 ± 0.2	0.1218
Marrow area (mm²)	1.1 ± 0.2	1.2 ± 0.3	1.3 ± 0.4	1.1 ± 0.2	0.1480
Cortical area (mm²)	0.87 ± 0.08	0.96 ± 0.08 ^*	0.95 ± 0.09 ^*	0.95 ± 0.10 ^*	0.0047
Cortical thickness (mm)	0.20 ± 0.01	0.21 ± 0.03 ^*	0.21 ± 0.02 ^*	0.22 ± 0.02 ^*	0.0066
Maximum cross-sectional moment of inertia (mm⁴)	0.34 ± 0.07	0.40 ± 0.08 ^*	0.41 ± 0.10 ^*	0.37 ± 0.07	0.0475
Minimum cross-sectional moment of inertia (mm⁴)	0.14 ± 0.03	0.16 ± 0.03	0.16 ± 0.04	0.15 ± 0.04	0.1689

Data presented as means and standard deviations. VEH, vehicle; ZOL, zoledronate; RAL-L, raloxifene 0.5 mg/kg; RAL-H, raloxifene 2.0 mg/kg; BV/TV, bone volume per tissue volume.

vs VEH;

vs ZOL.