Table 4. Diagnostic accuracy measures for diagnosing LMS using different criterions to signify LMS.
Number of MR features present in a lesion | Reader | Sensitivity [95%CI; N] | Specificity [95%CI; N] | PPV [95%CI; N] | NPV [95%CI; N] | Accuracy [95% CI; N] |
---|---|---|---|---|---|---|
≥1 feature | 1 | 1.00 [0.82-1.00;19/19] | 0.55 [0.32-0.76;12/22] | 0.66 [0.46-0.82;19/29] | 1.00 [0.74-1.00;12/12] | 0.76 [0.60-0.88;31/41] |
2 | 1.00 [0.82-1.00;19/19] | 0.59 [0.36-0.79;13/22] | 0.68 [0.48-0.84;19/28] | 1.00 [0.75-1.00;13/13] | 0.78 [0.62-0.89;32/41] | |
≥2 features present | 1 | 1.00 [0.82-1.00;19/19] | 0.82 [0.60-0.95;18/22] | 0.83 [0.61-0.95;19/23] | 1.00 [0.81-1.00;18/18] | 0.90 [0.77-0.97;37/41] |
2 | 1.00 [0.82-1.00;19/19] | 0.77 [0.55-0.92;17/22] | 0.79 [0.58-0.93;19/24] | 1.00 [0.80-1.00;17/17] | 0.88 [0.74-0.96;36/41] | |
≥3 features present | 1 | 1.00 [0.82-1.00;19/19] | 0.95 [0.77-1.00;21/22] | 0.95 [0.75-1.00;19/20] | 1.00 [0.84-1.00;21/21] | 0.98 [0.87-1.00;40/41] |
2 | 0.95 [0.74-1.00;18/19] | 1.00 [0.85-1.00;22/22] | 1.00 [0.81-1.00;18/18] | 0.96 [0.78-1.00;22/23] | 0.98 [0.87-1.00;40/41] | |
4 features present | 1 | 0.58 [0.33-0.80;11/19] | 1.00 [0.85-1.00;22/22] | 1.00 [0.72-1.00;11/11] | 0.73 [0.54-0.88;22/30] | 0.80 [0.65-0.91;33/41] |
2 | 0.58 [0.33-0.80;11/19] | 1.00 [0.85-1.00;22/22] | 1.00 [0.72-1.00;11/11] | 0.73 [0.54-0.88;22/30] | 0.80 [0.65-0.91;33/41] |
Note: MR magnetic resonance, PPV positive predictive value, NPV negative predictive value, CI confidence interval