Table 3. Molecular analyses on EBUS-TBNA.

Starting material	No. of cases	Cytopathological diagnosis	Mutational analysis method		Mutational analysis					FISH analysis
					EGFR	KRAS	BRAF	NRAS		ALK	ROS1	MET
EBUS-TBNA	1	NSCLC	–		IN	–	–	–		–	–	–
	7	NSCLC	Pyr		P	–	–	–		–	–	–
	1	NSCLC	Pyr		P	P	–	–		–	–	–
	4	NSCLC	Pyr		P	–	–	–		P	–	–
	18	NSCLC	MS		P	P	P	–		–	–	–
	2	Melanoma	MS		–	–	P	P		–	–	–
	16	NSCLC	MS		P	P	P	–		P	–	–
	2	NSCLC	MS		P	P	P	–		IN	–	–
	3	NSCLC	MS		P	P	P	–		P	P	–
	2	NSCLC	MS		P	P	P	–		P	P	P

P, successfully performed analyses; IN, inadequate specimens; –, tests not requested by the clinicians; MS, MALDI-TOF MS; Pyr, pyrosequencing. EBUS-TBNA, endobronchial ultrasonography with transbronchial needle aspiration; EGFR, epidermal growth factor receptor; KRAS, Kirsten rat sarcoma; BRAF, v-Raf murine sarcoma viral oncogene homolog B; NRAS, neuroblastoma RAS viral oncogene homolog; ALK, anaplastic lymphoma kinase; ROS1, c-ros oncogene 1; MET, met proto-oncogene.