Table 5. Type of EGFR, KRAS and BRAF mutations detected in NSCLC and metastatic melanoma specimens.
Mutation type | NSCLC | Metastatic melanoma | |||
---|---|---|---|---|---|
No. of cases | No. positive | No. of cases | No. positive | ||
EGFR L858R, exon 21 | 53 | 4 | – | – | |
KRAS G12C, exon 2 | 42 | 2 | – | – | |
KRAS G12V, exon 2 | 42 | 2 | – | – | |
KRAS G13C, exon 2 | 42 | 2 | – | – | |
BRAF V600E, exon 15 | 41 | 1 | 2 | 1 |
NSCLC, non-small cell lung cancer; EGFR, epidermal growth factor receptor; KRAS, Kirsten rat sarcoma; BRAF, v-Raf murine sarcoma viral oncogene homolog B.