FIGURE 6.
Effects of aging and leonurine on mitochondrial damage in ischemic muscles. (A–C) Quantification of mRNA expression of mitochondrial component, nicotinamide adenine dinucleotide dehydrogenase subunit 1 (ND1; A) and cytochrome b (Cyt-b; B) assessed by quantitative realtime PCR. (C) Quantification of Long-extension (LX)-PCR and short-extension (SX)-PCR of mtDNA ratio. Data are mean ± SEM. ∗∗p < 0.01 vs. young group; ##p < 0.01 vs. old group. n = 6–8/group.