Table 4.

Change from baseline in COPD assessment test scores

	Indacaterol, mean ± SD	Placebo, mean ± SD	Treatment difference, mean (95% CI)	P-value
ITT
Visit 2	15.40±7.31	16.24±9.30	−0.84 (−3.69, 2.00)	0.559
Visit 4a	15.65±8.08	17.89±8.53	−2.25 (−5.09, 0.59)	0.120
Difference (Visit 4 – Visit 2)	0.25±5.90	1.80±7.65	−1.55 (−3.88, 0.78)	0.192
PP
Visit 2	15.37±8.03	16.30±8.72	−0.93 (−4.37, 2.51)	0.592
Visit 4	15.31±8.68	18.63±8.48	−3.31 (−6.85, 0.22)	0.066
Difference (Visit 4 – Visit 2)	−0.06±6.12	2.33±8.22	−2.38 (−5.33, 0.56)	0.121

Note:

^aLOCF was used to impute missing values at Visit 4.

Abbreviations: CI, confidence interval; ITT, intent-to-treat; LOCF, last observation carried forward; PP, per protocol; SD, standard deviation.