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. 2017 May 29;11:1623–1642. doi: 10.2147/DDDT.S136692

Scheme 6.

Scheme 6

Plausible scenario to account for the formation of (1A–15A) and same for the preparation of (1B–15B).

Note: Substituted α-tetralone (a), substituted aromatic aldehydes (b) and distinctive 2-aminothiazoles (c).