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. 2017 May 29;11:1623–1642. doi: 10.2147/DDDT.S136692

Scheme 3.

Scheme 3

One-pot efficient synthetic route to the titled compound (1B–15B).

Note: Substituted α-indanone (a′), substituted aromatic aldehydes (b) and distinctive 2-aminothiazoles (c).

Abbreviations: EtOH, ethanol; p-TSA, p-toluenesulfonic acid.