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. 2017 May 30;8:15622. doi: 10.1038/ncomms15622

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Copyright © 2017, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Assembly of the isomiR-4534/AGO1 complex on sense promoter-associated RNA silences CDH1 transcription. SNP rs16260 influences, through changes in the sense transcript secondary structure, the loading of isomiR-4534/AGO1 and the assembly of the transcriptional silencing complex.