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. 2017 May 30;8:15527. doi: 10.1038/ncomms15527

Figure 2. Comparable performance of Addict F1 and Non-addict F1 rats in basal and cocaine-induced locomotion activity and food self-administration.

Figure 2

(a) Open field test. Total distance, Student's t-test, t (64)=0.872, P=0.386. Time in centre, Student's t-test, t (64)=1.197, P=0.236. Entries to centre, Student's t-test, t (64)=0.142, P=0.887. Non-addict F1, n=37; Addict F1, n=29. (b) Sensitivity to cocaine-induced locomotor activity. Two-way RM ANOVA, FGroup × Dose (4, 80)=0.734, P=0.571. Non-addict F1, n=11; Addict F1, n=11. (c) Food self-administration test. Lever press, Group × FR, MMRM, χ2 (1)=0.19, P=0.663. Break point, Mann–Whitney Rank-Sum Test, Z=1.039, P=0.299. Non-addict F1, n=12; Addict F1, n=17. Data are expressed as mean±s.e.m.