Figure 4. Allelic regions of Vκ promotor chromatin accessibility.

ATAC-seq profiles of chromatin accessibility in pre-B-cell clones and ex-vivo sorted BM pre-B cells at representative Vκ segments V_1–135, V_9–134, V_2–112 and V_2–137. Total reads, regardless of allelic origin are marked in green, reads identified as originating from the B6 allele based on SNPs are marked in blue, reads identified as originating from the Cast allele based on SNPs are marked in red. It is not possible to identify the allelic source of all mapped reads, as exemplified by V_2–137. Genomic intervals and tracks displayed on UCSC genome browser, mouse build mm10.