Skip to main content
. 2017 Jun 6;8:334. doi: 10.3389/fphar.2017.00334

FIGURE 1.

FIGURE 1

Berberine ameliorates the fear-memory deficit in DM rats. (A) Experiment protocol. Rats were exposed to an inescapable chamber and with different cue and contextual fear, and the freezing percent was recorded during the 3 days. (B) The freezing percent in the 1st day after 3 days acclimatization. (C) The freezing percent in the 1st day after the training trail of 1.5 h later to detect the short-term memory. (D,E) The freezing percent in the 2nd (D) and 3rd (E) day after the training trail to further appraise the long-term memory, and assessed the protection of BBr. P < 0.05 vs. NOR; ∗∗P < 0.01 vs. NOR; ∗∗∗P < 0.001 vs. NOR; #P < 0.05 vs. DM; ##P < 0.01 vs. DM; n = 8∼12.