Table 1.
BL | HFD | HFD + P | |
---|---|---|---|
Plasma Lipids (mM) | |||
Total cholesterol | 2.89 ± 0.09 | 3.64 ± 0.33** | 3.15 ± 0.38# |
Very low-density lipoprotein/low-density lipoprotein | 0.41 ± 0.10 | 0.79 ± 0.07*** | 0.69 ± 0.09*** |
High-density lipoprotein | 1.73 ± 0.14 | 2.04 ± 0.23p=0.054 | 1.79 ± 0.26 |
Triglycerides | 0.76 ± 0.14 | 0.80 ± 0.15 | 0.71 ± 0.12 |
Plasma Cytokines (pg/ml) | |||
Interferon-γ | 0.59 ± 0.26 | 0.61 ± 0.39 | 0.97 ± 0.41 |
Interleukin-10 | 14.23 ± 4.26 | 12.83 ± 2.56 | 15.18 ± 3.83 |
Interleukin-12p70 | 51.11 ± 54.01 | 30.05 ± 32.06 | 19.80 ± 12.17 |
Interleukin-1β | 0.84 ± 0.59 | 0.74 ± 0.49 | 0.60 ± 0.24 |
Interleukin-2 | 3.24 ± 1.46 | 2.84 ± 1.41 | 2.14 ± 0.60 |
Interleukin-4 | 0.72 ± 0.57 | 0.43 ± 0.37 | 0.37 ± 0.13 |
Interleukin-5 | 2.95 ± 0.64 | 3.14 ± 1.20 | 3.18 ± 0.34 |
Interleukin-6 | 6.37 ± 2.13 | 10.22 ± 8.47 | 10.39 ± 3.80 |
Keratinocyte chemoattractant/growth-regulated oncogene | 63.19 ± 15.62 | 75.36 ± 14.15 | 89.62 ± 21.26* |
Tumor Necrosis Factor-α | 10.7 1 ± 1.27 | 11.47 ± 2.59 | 15.34 ± 5.16 |
Data represent the means ± standard deviation of 6 mice per group. Values of p were determined using one-way ANOVA with Tukey’s (equal variance) or Dunnett’s T3 (unequal variance) post-hoc analysis where ∗ p < 0.05, ∗∗ p < 0.01, and ∗∗∗ p < 0.001 versus the BL group; # p < 0.05 versus the HFD group. Values of p compared to the BL group are stated where appropriate.