Table 3.
Alignment results of data elements between CDASH Medication and TCGA Clinical Pharmaceutical
| Question Text | Prompt Data Element Name | TCGA CDEs or Enriched Data Elements |
|---|---|---|
| Were any medications taken? | Any meds | Administered |
| What is the medication/treatment identifier? | CM number | Identifier; Unique Identifier |
| What was the term for the medication/therapy taken? | Medication or Therapy | Drug Name |
| Did the subject take < specific medication/treatment > ? | <specific medication/treatment> | Cytokine Administered; Placebo Bevacizumab Administered; HER2/neu Administered |
| What were the active ingredients? | Active Ingredients | PubChem Compound Identifier |
| For what indication was the medication/therapy taken? | Indication | Indication |
| What was the ID for the adverse events(s) for which the medication was taken? | AE ID | Toxicity Description; Toxicity Grade |
| What was the ID of the medical history condition(s) for which the medication was taken? | MH ID | |
| What was the individual dose of the medical/therapy? | Dose | Prescribed Dose |
| What was the total daily dose of the medication therapy? | Total Daily Dose | Cumulative Agent Total Dose |
| What was the unit of the medical/therapy? | Dose Unit | Total Dose Units;Prescribed Dose Units |
| What was the dose form of the medication/therapy? | Dose Form | Pharmaceutical Dosage Form Code |
| What was the frequency of the medication/therapy? | Frequency | Number Cycles |
| What was the route of administration of the medication/therapy? | Route | Route Of Administration |
| What was the start date of the medication/therapy? | Start Date | Year Of Drug Therapy Start;Month Of Drug Therapy Start; Day Of Drug Therapy Start |
| What was the start time of the medication/therapy? | Start Time | Agent Administered Begin Time |
| Was the medication/therapy taken prior to the study? | Taken Prior to Study? | Prior Therapy Treatment Regimen |
| What was the end date of the medication/therapy? | End Date | Year Of Drug Therapy End; Month Of Drug Therapy End; Day Of Drug Therapy End |
| What was the end time of the medication/therapy? | End Time | Agent Administered End Time |
| Is the medication/therapy still ongoing? | Ongoing | Therapy Ongoing |
Bold italic font indicates an enriched data element