Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Jun 6;5:17016. doi: 10.1038/boneres.2017.16

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2017 The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

SOST expression partially rescues cancellous but not cortical bone phenotype caused by Bmpr1a deletion. (a) Serum CTX-I assays, n=3. (b) Representative images of H&E stained sections of the distal femur at P33. Boxed regions are shown at a higher magnification in lower panels. Arrow denotes accumulation of osteoblasts. (c and d) H&E staining (c) and quantification of osteocyte density (d) in cortical bone of the femur at P33. *P<0.001, two-way ANOVA, n=3. (e) Representative images of calcein double labeling at periosteal surface in P33 littermate mice. (f) Quantification of MAR. *P<0.001, owo-way ANOVA, n=3. ANOVA, analysis of variance; B, bone; M, marrow; SOST, sclerostin.