Table 4.
Associations between peritonitis and mortality using the COX proportional hazards regression models
| Univariate model | Multivariate model | |||
|---|---|---|---|---|
| HR (95% CI) | P value | HR (95% CI) | P value | |
| All-cause mortality | ||||
| Peritonitisa | 2.19 (1.68–2.85) | <0.001 | 1.95 (1.46–2.60) | <0.001 |
| Age (per year increase) | 1.07 (1.06–1.08) | <0.001 | 1.04 (1.03–1.05) | <0.001 |
| Male gender | 0.96 (0.75–1.23) | 0.756 | 1.05 (0.80–1.37) | 0.750 |
| Diabetes mellitus | 3.76 (2.95–4.80) | <0.001 | 1.97 (1.48–2.63) | <0.001 |
| History of CVD | 4.17 (3.23–5.39) | <0.001 | 2.01 (1.48–2.74) | <0.001 |
| 24-h urine output (per 100 ml increase) | 0.93 (0.90–0.95) | <0.001 | 0.97 (0.94–0.99) | 0.023 |
| Hemoglobin (g/dL) | 0.78 (0.73–0.82) | <0.001 | 0.83 (0.77–0.88) | <0.001 |
| Serum phosphorus (mg/dL) | 1.20 (1.13–1.28) | <0.001 | 1.16 (1.08–1.25) | <0.001 |
| Serum albumin (g/dL) | 0.39 (0.31–0.49) | <0.001 | 0.83 (0.64–1.07) | 0.155 |
| Infection-related mortality | ||||
| Peritonitisa | 6.00 (3.26–11.03) | <0.001 | 4.94 (2.47–9.86) | <0.001 |
| CV mortality | ||||
| Peritonitisa | 2.05 (1.43–2.93) | <0.001 | 1.90 (1.28–2.81) | <0.001 |
aPeritonitis was parameterized as a time-dependent covariate. Multivariable models for peritonitis were adjusted for age, sex, diabetes, history of CVD, 24-h urine output, hemoglobin, serum phosphorus, and serum albumin.
CVD cardiovascular disease, PD peritoneal dialysis