Table 5.
Stratified analysis by follow-up time period for mortality for patients who experienced peritonitis in the COX proportional hazards regression models
| Time period (years) | No. of patients | No. of deaths | Univariate model | Multivariate model# | ||
|---|---|---|---|---|---|---|
| HR (95% CI) | P value | HR (95% CI) | P value | |||
| All-cause mortalitya | ||||||
| Overall | 1321 | 261 | 2.19 (1.68–2.85) | <0.001 | 1.95 (1.46–2.60) | <0.001 |
| ≤2 years | 1321 | 131 | 1.19 (0.75–1.88) | 0.465 | 0.80 (0.46–1.38) | 0.421 |
| >2 years | 939 | 130 | 4.65 (3.26–6.63) | <0.001 | 3.98 (2.70–5.86) | <0.001 |
| Infection-related mortalityb | ||||||
| Overall | 1321 | 46 | 6.00 (3.26–11.03) | <0.001 | 4.94 (2.47–9.86) | <0.001 |
| ≤2 years | 1321 | 16 | 2.25 (0.79–6.43) | 0.129 | 1.06 (0.26–4.32) | 0.932 |
| >2 years | 939 | 30 | 12.47 (5.18–30.01) | <0.001 | 9.33 (3.56–24.47) | <0.001 |
| CV mortalityc | ||||||
| Overall | 1321 | 147 | 2.05 (1.43–2.93) | <0.001 | 1.90 (1.28–2.81) | 0.001 |
| ≤2 years | 1321 | 75 | 1.05 (0.55–1.99) | 0.882 | 0.69 (0.32–1.48) | 0.339 |
| >2 years | 939 | 72 | 4.51 (2.80–7.27) | <0.001 | 4.13 (2.46–6.94) | <0.001 |
Note: Peritonitis was parameterized as a time-dependent covariate
#Multivariable models were adjusted for age, sex, diabetes, history of CVD, 24-h urine output, hemoglobin, serum phosphorus, and serum albumin.
aOverall test for interaction of peritonitis and time period, Wald 2 = 8.23, P = 0.004; all-cause mortality.
bOverall test for interaction of peritonitis and time period, Wald2 = 6.02, P = 0.014; infection-related mortality.
cOverall test for interaction of peritonitis and time period, Wald2 = 2.32, P = 0.128; CV mortality